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Lexxema Cream in Spain: What It Is

Dr. Pedro Yelamo Vera
Medical Review

Medically Reviewed by Dr. Pedro Yelamo Vera, MD

Licensed Physician No. 484814280 · Official Medical College of Bizkaia (Spain)Last reviewed: 2 October 2026

5.0 on Google16 reviews

Lexxema is methylprednisolone aceponate, a steroid cream sold elsewhere as Advantan. What it treats, when it makes skin worse and when to see a doctor.

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Lexxema is methylprednisolone aceponate, a steroid cream for inflamed skin. In other countries the same medicine is sold as Advantan.

  • What it is used for: eczema and dermatitis, including atopic and contact dermatitis.
  • What it is not for: skin infections caused by fungi, bacteria or herpes, acne, rosacea or a rash around the mouth; it can make these worse.
  • Precautions: use a thin layer on the affected area only, for the time prescribed. On the face and in skin folds, courses should be short. Do not cover it with dressings unless told to.
  • Do you need a prescription? Yes.
  • See a doctor if: it has not improved in one to two weeks, the area weeps or hurts, or the eczema returns when you stop.

This is general information and does not replace the package leaflet or the advice of your doctor or pharmacist. If you need an assessment, you can book a video consultation or read about eczema. This service is for urgent, non-emergency care; in an emergency, call 112.

Medical Citations & Sources

This content is written and reviewed by a licensed physician with reference to the following official health authorities.

  1. World Health Organization (WHO)
  2. Spanish Ministry of Health (Ministerio de Sanidad)
  3. European Centre for Disease Prevention and Control (ECDC)
  4. NHS — Health A to Z

Dr. Pedro Yelamo Vera

General Practitioner & Telemedicine Specialist · License No. 484814280

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